ROLE OF RADIOTHERAPY IN THYROID CARCINOMA
To reach the studies
Please to enroll your anaplastic thyroid cases; click here: ANAPLASTIC

Please to enroll your non anaplastic thyroid cases; click here: NON ANAPLASTIC

Synopsis
NON-anaplastic thyroid cancers (follicular, papillary, medullary, insular=poorly differentiated) are relatively common tumors but are irradiated in exceptional situations only. While irradiation of cases with radioiodin-negative massive extrathyroidal extension is consensual, other indications are highly controversial. The sole randomized study conducted to date on that topic was terminated early because of slow accrual. Several retrospective studies raise the question of irradiation for poor prognostic histological variants (such as Hurtle-oncocytic, tall cell variants..), for incomplete resection, for extensive extracapsular nodal disease .... Because a randomized trial is not feasible, we here propose a retrospective study, with the aim of collecting ≥ 200 cases irradiated between 2000 and 2015.

We also propose a study of anaplastic = undifferentiated thyroid carcinomas for patients irradiated between 2000 and 2015 to better define the role and type of neoadjuvant / adjuvant chemotherapy in association with chemoradiation.